It’s a familiar image we might attribute to stereotype: a sluggish, maybe portly individual lying prostrate on the couch, his/her front littered with Dorito crumbs. Could there, however, be truth behind the picture? Is there indeed a connection between incessant snacking and chronic slothdom? Or considered another way, is there a connection between fasting and being active?
For decades now, conventional wisdom has told us that we should eat regularly throughout the day to keep our blood sugar steady. With three regular meals and at least two snacks, we’re counselled to keep our bodies in a perpetual full tummy state. However, newer research, including this month’s study from ETH Zurich(Swiss Federal Institute of technology, from The Journal of Biological Chemistry), questions this assumption. Below is a part of the study(http://www.jbc.org/content/283/24/16940.full):
Scientists focused on the opposing relationship between a transcription factor, Foxa2, and insulin. Foxa2 is found in both the liver and the hypothalamus, the central command for hunger regulation. It has a hand in the expression of two eating and physical activity related hormones (based on the journal: neuropeptides, melanin-concentrating hormone (MCH) and orexin). When insulin (a hormone that help stores glucose (or simply sugar) in your liver) is present, as it is during and after eating, Foxa2 and the related MCH and orexin are reduced. However, fasting showed consistently high levels of Foxa2, MCH and orexin. The researchers then found that the obese showed reduced Foxa2, MCH, and orexin, regardless of whether they had eaten or not. When the scientists bred mice with continually active Foxa2 (immune to the counter effect of insulin), these mice showed high levels of MCH and orexin – and a correspondingly high level of physical activity whether they had eaten or not. The specially bred mice had low body fat as well as higher muscle mass.
Consider this study a nail in the coffin for saying fasting makes you tired. Fasting, even short, between-meal breaks, promotes activity-inducing effects. A simple survival principle explains this: a hungry animal needs to get up and move to find food. On the other hand, if we are constantly swimming in the insulin of eating and post-eating states, we’re undermining our own motivation (and biochemical stimulus) to get up and burn off what we just ate.
Many of those who preaches good health encourages us to never skip breakfast, bring along a mid-morning snack, make time for a good lunch, grab a mid-afternoon nibble and then have a good dinner. Oh, and if you can’t sleep, you’re supposed to have warm milk and a banana before bed. Our bodies are either eating or processing what we ate. There’s never a recovery period. We’re so focused on the stable” blood sugar that we’ve forgotten that there’s more to the biochemical story of balanced energy. We make ourselves feel perpetually full to the exclusion of feeling anything else.
We continually raise our blood sugar and insulin levels and, in doing so, turn off the body’s chance to activate or up regulate other key substances that promote energy balance – and as this study shows, the physiological motivation to be active. So guys, simple advice: skip the snack. & try develop a habit of fasting every week eg. Monday & Thursday ;)
AWESOME!!!
AWESOME!!!
“The best of all medicines is resting and fasting” -Benjamin Franklin





